Effects of 17β-estradiol on leptin signaling in anterior pituitary of ovariectomized rats
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چکیده
منابع مشابه
Effects of 17β-estradiol on leptin signaling in anterior pituitary of ovariectomized rats
Leptin is secreted predominantly by adipocytes and exerts its role mainly by interaction with the long form of leptin receptor (LEPR_V2). It has been identified that LEPR_V2 is widely distributed in various tissues, including the anterior pituitary. Cross-talk between leptin and estrogens has been indentified. Estrogen is known to modulate the tissue-specific expression of LEPR_V2 and leptin in...
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The effects of chronic treatment with 17β-estradiol on baroreflex control of sympathetic activity were examined in conscious unrestrained ovariectomized rats. Baroreflex function was evaluated by logistic sigmoidal analysis of the relationships between changes in mean arterial pressure (MABP) and changes in heart rate (HR) and splanchnic nerve activity (SNA) when MABP was rapidly increased to 1...
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The effects of 17β-estradiol (E2) on sympathetic activity were examined in conscious unrestrained ovariectomized rats, instrumented under methohexital anesthesia to record mean arterial pressure (MABP), heart rate (HR), renal nerve activity (RNA), and splanchnic nerve activity (SNA) 1 day before the experiment. Injection of E2 (150 μg/kg iv) caused reductions ( P < 0.01) in RNA (29 ± 6%), SNA (...
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ژورنال
عنوان ژورنال: Experimental Animals
سال: 2017
ISSN: 1341-1357,1881-7122
DOI: 10.1538/expanim.16-0087